Thymic epithelial cell line
WebbThe major histocompatibility complex (MHC)-restricted presentation of self-peptides, generated from tissue-specific antigens, by thymic epithelial cells (TECs) is essential for … WebbThymic epithelium is organized in a highly connected three-dimensional network through which thymocytes differentiate. The molecular mechanisms underlying this organization …
Thymic epithelial cell line
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Webb12 apr. 2024 · The thymus is a primary lymphoid organ uniquely specialised for the production of T-cells. During intrathymic T-cell development, thymic epithelial cells … Webb1 feb. 2001 · The results demonstrate that the thymic epithelial cell line IT-76MHC produces modest thymocyte survival factors as well as a growth suppressor, and that IT- 76MHC cells have the ability to induce transplantation tolerance probably through their expression of MHC class I and II molecules. Interactions between thymocytes and …
WebbThe transcription factor FOXN1 is essential for fetal thymic epithelial cell (TEC) differentiation and proliferation. Postnatally, Foxn1 levels vary widely between TEC … Webb13 aug. 2024 · The thymus is the primary lymphoid organ specialized in the development of a diverse repertoire of non-self-reactive T lymphocytes. Thymic epithelial cells (TEC)s …
WebbThymus-derived stromal cell lines. We derived stromal cell lines from mouse thymus using methods previously established for bone marrow stroma. Two main morphologically … Webb1 juni 1994 · The thymic stromal microenvironment is required for the generation of immunocompetent T lymphocytes. However, the different thymic stromal cell types have …
WebbCELL LINE TYPES. The 1055 different cell lines used in the Cell Line section have been selected to represent various cell populations in different tissue types and organs of the human body. Most of the cell lines used are human cancer cell lines (n = 985). In addition to the cancer-derived cell lines, there is a number of cell lines that have ...
Webb1 juni 2002 · We have therefore applied criteria predicted of thymic epithelial progenitor cells (TEPC) and their markers to MTS20 + 24 + cells within the murine thymic primordium. Furthermore, we have conducted an extensive phenotypic characterization of the E11.5 and E12.5 thymic primordia and of embryonic thymic MTS20 + 24 + cells. fifa games free androidWebbEphrin receptors (Ephs) are receptor tyrosine kinases (RTKs) implicated in tissue development and homeostasis, and they are aberrantly expressed in tumors. Here, … fifa games free downloadWebb24 nov. 2024 · The thymic microenvironment is mainly comprised of thymic epithelial cells, the cytokines, exosomes, surface molecules, and hormones from the cells, and plays a vital role in the development, differentiation, maturation and homeostasis of … fifa games free playWebb23 mars 2024 · Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells, researchers report March 23 in the journal Stem Cell Reports. The ... griffith bricks and paversWebb18 juni 2024 · Particularly important in the choreography of T cell selection are thymic epithelial cells (TECs), which represent a key component of the thymic stromal microenvironment. TECs are typically subdivided into functionally distinct cortical (cTEC) and medullary (mTEC) lineages ( 1 ). griffith bricks \u0026 paversWebbA thymic epithelial cell (TEC) line (B/c. TEC-L1) was established from a normal thymus of a 4-week BALB/c mouse. The B/c. TEC-L1 had an epithelial morphology showing a contact … fifa game shading peopleWebb25 maj 2024 · Differentiation of thymic epithelial cells (TECs) is dependent on the Foxn1 transcription factor 28, 29, 30, 31, 32, 33, 34, 35, and defects in epithelial specification and development are... griffith bridge club