Pttg1ip knockout mouse
WebKnockout Mice Request Consultation Genetically engineered mouse and rat models can be broadly grouped into three categories: knockouts, knock-ins, and transgenics. The intent of a knockout model is to generate an animal … WebStep 1: Generating a targeting vector. The first step in making a knockout mouse is identifying the region of the gene that will be deleted. Because the entire mouse genome sequence is already ...
Pttg1ip knockout mouse
Did you know?
WebOct 27, 2024 · PTTG1IP promotes the shift of securin from the cell cytoplasm to the nucleus, allowing the interaction between separase and securin. PTTG1IP overexpression has been previously observed in malignant disease, e.g. in breast carcinoma. However, the prognostic value of PTTG1IP in breast carcinoma patients has not previously been revealed. WebThe benefits of using the knockout or knock-in mouse model to study disease include its endless applications and relative ease of manipulation. Knockout and Knock-in Technology Highlight: CRISPR/Cas9. Indeed, knockout and knock-in mouse models have been developed to both understand the mechanisms of diseases and discover drugs to treat them.
WebUse Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed. WebJun 15, 2012 · Knockout Mouse Project Meetings, Papers and News. Nature News: Mouse Library Set to be Knockout June 15, 2011 Nature Article: A conditional knockout resource for the genome-wide study of mouse gene function June 15, 2011 NOT-DA-08-015 [grants.nih.gov]: NIH Grantees can now purchase Lexicon mice with funds from grants …
WebOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach … WebUse Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed.
WebProduction and phenotyping are currently not planned for a knockout strain of this gene. Btbd35f15 Name: BTB domain containing 35, family member 15 Synonyms: Gm2913. View Data Order Mice. ... PTTG1IP family member 2 Synonyms: LOC381716, 1700015F17Rik. View Data Order Mice. Log in to follow
WebAbout KOMP. The Knockout Mouse Program (KOMP2) is an NIH initiative that, together with the other members of the International Knockout Mouse Consortium (IKMC), aims to generate a public resource comprised of knockout information for all protein-coding genes in the mouse genome. For more details, see the NIH KOMP2 Home Page. movie death by televisionWebPTTG1IP. Pituitary tumor-transforming gene 1 protein-interacting protein (PTTG1), also known as PTTG1-binding factor (PBF), is a poorly characterised protein that in humans is … heather gidding ncirsWebJan 1, 2008 · Description. Identified through its interaction with pituitary tumor transforming 1 (PTTG), the PTTG1IP protein is 180 amino acids long with a molecular mass of approximately 25 kDa. A putative signal peptide exists at the N-terminus (1-32). A domain of unknown function common to plexins, semaphorins and integrins (PSI) is located … movie death huntWebNational Center for Biotechnology Information heather gierkeWebFeb 10, 2024 · A key finding supporting a causal role of the immune system in the pathogenesis of hypertension is the observation that RAG1 knockout mice on a C57Bl/6J background (B6.Rag1 −/ −), which lack functional B … heather gibson wife of richard griffithsWebIn the 10 years since the first knockout of the mouse p53 tumor suppressor gene (designated Trp53) was published, much has been learned about the contribution of p53 … heather gibson richard griffithsWebOct 27, 2024 · Pituitary tumour transforming gene 1 interacting protein (PTTG1IP, also PTTG1-binding factor, PBF) is an oncogene, originally detected as a 22 kDa protein binding to securin [1, 2].Securin, the protein product of PTTG1, in turn, is a proto-oncogene first described in rat pituitary tumour cells [].Both proteins are key actors in the complex … heather gibson realtor