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Webb29 mars 2024 · HM43239 is a potent FLT3 inhibitor and shows effectiveness in AML with FLT3 mutations. HM43239 is an orally active and selective FLT3 inhibitor with IC 50 of 1.1 nM for the FLT3 wild type. In addition, it shows IC 50 s of 1.8 nM (FLT3 ITD mutants) and 1.0 nM (FLT3 D835Y mutants), respectively. Moreover, it inhibits the kinase activity of … Webb16 mars 2024 · Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications Impact Factor: 2.663 / 5-Year Impact Factor: 2.459 JOURNAL HOMEPAGE SUBMIT PAPER Add email alerts You are adding the following journal to your email alerts New content forward in spanish translation
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