Mineralocorticoid receptor antagonists 翻译
Web4 mei 2024 · In particular, mineralocorticoid receptor antagonists (MRAs), by means of natriuresis and contraction of plasma volume, stimulate RAAS activation, thus renin … WebLimitations of current steroidal mineralocorticoid receptor (MR) antagonists have stimulated the search for a new generation of molecules. We screened for novel …
Mineralocorticoid receptor antagonists 翻译
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Web12 mrt. 2024 · Chronic kidney disease (CKD) represents a global health concern, and its prevalence is increasing. The ultimate therapeutic option for CKD is kidney transplantation. However, the use of drugs that target specific pathways to delay or halt CKD progression, such as angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and … Web受體結合 (mineralocorticoid receptor)， 因而可以改善嚴重心衰竭病人的治療結 果。醛固酮是由腎上腺皮質合成分泌， 為腎素- 血管收縮素- 醛固酮系統(renin-agiotensin …
Web文档翻译; 收录引证; 论文 ... Mineralocorticoid Receptor Antagonists. ... Heart FailureLipiecVasopressin receptor antagonists; 20. Lipid Lowering Treatment and Follow Up in Recent Post Acute Coronary Syndrome Patients: Real-World Evidence from the Multicenter Observational Prospective ... Web22 nov. 2012 · In the presence of salt, aldosterone causes hypertension and organ damage via the mineralocorticoid receptor (MR) through various mechanisms. MR …
Web1 jan. 2007 · The last decade has witnessed tremendous progress in the understanding of the mineralocorticoid receptor (MR), ... Role of Mineralocorticoid Receptor Antagonists in Diabetic Kidney Dise... Crossref . Show details . miR-324-5p … WebMineralocorticoid Receptor Antagonists Name Mineralocorticoid Receptor Antagonists Accession Number DBCAT000844 Description Drugs that bind to and block the activation of MINERALOCORTICOID RECEPTORS by MINERALOCORTICOIDS such as ALDOSTERONE. ATC Classification C — CARDIOVASCULAR SYSTEM C03 — …
Web参考「Mineralocorticoid Antagonists」学术论文例句，一次搞懂! Introduction to Mineralocorticoid Antagonists (盐皮质激素拮抗剂) 学术写作例句词典 Manuscript …
http://www.ichacha.net/mineralocorticoid%20receptor.html banks 1900Web6 aug. 2012 · Modulating Mineralocorticoid Receptor with Non-steroidal Antagonists. New Opportunities for the Development of Potent and Selective Ligands without Off-Target Side Effects. Journal of Medicinal Chemistry 2024, 60 (7) , 2629-2650. banks 19252Web29 mei 2024 · Activation of the mineralocorticoid receptor (MR) plays important roles in both physiological and pathological events. Blockade of MR signaling with MR antagonists (MRAs) has been used clinically to treat kidney and cardiac disease associated with hypertension and other chronic diseases, resulting in suppression of fibrosis in these … banks 19125WebEndocrine Mineralocorticoids & Mineralocorticoid Antagonists inhibitor Fludrocortisone Systemic fungal infections Spironolactone Hyperkalemia, Addison disease Concomitant use: eplerenone PATIENT EDUCATION Mineralocorticoid antagonists: avoid potassium supplements, potassiumcontaining salt substitutes, potassium-rich diets, ↑ K+ drugs (e.g. … banks 1915Mineralocorticoid receptor antagonists are diuretic drugs that work primarily on the kidneys. They decrease sodium reabsorption, which leads to increased water excretion by the kidneys. By regulating water excretion, mineralocorticoid receptor antagonists lower blood pressure and reduce fluid around … Meer weergeven An antimineralocorticoid, also known as a mineralocorticoid receptor antagonist (MRA or MCRA) or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at Meer weergeven Increased urination is a commonly reported side effect, particularly during the initial phase following treatment initiation; this is … Meer weergeven When comparing the pharmacokinetic properties of spironolactone and eplerenone, it is clear that the two drugs differ. Spironolactone has … Meer weergeven The main goal of the identification of the first aldosterone antagonists, which happened during the 1950s, was to identify … Meer weergeven Aldosterone is a mineralocorticoid which is synthesized in the adrenal glands. When aldosterone is secreted from the adrenal glands, it binds to the mineralocorticoid receptor in the renal tubule cell and forms a complex. This complex enhances transcription of … Meer weergeven Spironolactone and Eplerenone competitively block the binding of aldosterone to the mineralocorticoid receptor and hindering the reabsorption of sodium and … Meer weergeven Members of this class in clinical use include: • Widespread use • Uncommon use (to date) Some drugs also have antimineralocorticoid … Meer weergeven banks 19128WebBrian L. Furman, in xPharm: The Comprehensive Pharmacology Reference, 2007 Introduction. Mineralocorticoid antagonists comprise a group of agents that … banks 19269WebMineralocorticoid antagonists comprise a group of agents that antagonize the action of the endogenous mineralocorticoid, aldosterone, at its receptors. Aldosterone regulates … banks 1927