Metal cation symporter zip14
WebCadmium (Cd) is a global pollutant that accumulates in the placenta and can cause placental dysfunction. Although iron transporters have been suggested to participate in placental Cd uptake, it is still unknown which transporters are actually Web1 mei 2008 · Tissues such as intestine and liver, located between the environment and the animal, show high levels of ZIP14; given the high affinity for ZIP14, Cd2+ is likely to act …
Metal cation symporter zip14
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WebDivalent metal transporter 1 (568 amino acids) transports iron into and out of the duodenal cytosol and into the hepatocyte and macrophages. 27 Divalent metal transporter 1 is active in a low-pH environment for efficient metal transport as H+/Fe2+ symporter. 25 Similarly, dietary heme can also be transported across the apical membrane by a yet unknown … WebZinc is a ubiquitous biological metal in all living organisms. ... -terminal CPALLY motif. Light green shading highlights loss of the conserved His, which in the case of ZnT10, ZIP8, and ZIP14 results in loss of zinc specificity. JBC REVIEWS: Zinc transporters 2 J. Biol ... protein family of cation diffusion facilitator (CDF) including ...
WebZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular … WebZIP14 is a transmembrane metal ion transporter that is abundantly expressed in the liver, heart, and pancreas. Previous studies of HEK 293 cells and the hepatocyte cell lines …
WebSlc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter. Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities … WebMouse Slc39a8 and Slc39a14 genes encode ZIP8 and ZIP14, respectively, which are ubiquitous divalent cation/(HCO 3 –) 2 symporters responsible for uptake of Zn 2+, Fe …
Web31 dec. 2024 · Cadmium (Cd) is an anthropogenic as well as a naturally occurring toxicant associated with prediabetes and T2DM in humans and experimental models of Cd exposure. However, relatively few studies have examined the …
WebDivalent metal transporter 1 (568 amino acids) transports iron into and out of the duodenal cytosol and into the hepatocyte and macrophages. 27 Divalent metal transporter 1 is … dj koze termineWebMetal cation symporter ZIP14 Definition: Electroneutral transporter of the plasma membrane mediating the cellular uptake of the divalent metal cations zinc, manganese and iron that are important for tissue homeostasis, metabolism, development and immunity. dj koze mixWebMetal cation symporter ZIP14 (Mouse) UniProt Q75N73 - S39AE_MOUSE Gene Slc39a14 View Product On Supplier's Website Request a Quote from Biorbyt Supplier provided … dj koze xtcWebThis gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an … dj kp remixWebZIP14 (SLC39A14)was shown to function as a zinc influx transporter in a temperature-dependant manner. PMID: 15642354; Zip14 expression is up-regulated through IL-6 … dj koze resWeb31 dec. 2024 · Cadmium (Cd) is an anthropogenic as well as a naturally occurring toxicant associated with prediabetes and T2DM in humans and experimental models of Cd … dj koze xtc sampleWeb10 apr. 2014 · gene encodes ZIP14, also a divalent metal/bicarbonate symporter 8. Both ZIP8 5 and ZIP14 9 transport an electroneutral complex, Zn 2+ /(HCO 3 − ) 2 , in which Zn 2+ dj kp da kid