Grn antibody
WebAug 4, 2010 · Grn expression in neurons increases as the cells mature, whereas expression in microglia varies with the cells' state of activation, being specifically upregulated in microglia in response to excitotoxic injury. Our results suggest that progranulin plays distinct roles in neurons and microglia, both of which likely contribute to overall ... WebNormal Function. The GRN gene provides instructions for making a protein called progranulin. This protein is primarily found in the membrane of cellular structures called …
Grn antibody
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WebInvitrogen Anti-Progranulin Monoclonal (2D4-2F1), Catalog # MA1-187. Tested in Western Blot (WB), Immunohistochemistry (Paraffin) (IHC (P)) and ELISA (ELISA) applications. This antibody reacts with Human samples. … WebGMAb provides excellent services related to monoclonal antibody technology, including the development of novel antibodies, immunoassay design and methods for antibody …
WebJul 4, 2024 · GR Antibody (H-300) is a rabbit polyclonal IgG; 200 µg/ml. epitope corresponding to amino acids 121-420 mapping within an internal region of GR of human … WebFor the independent antibodies validation the evaluation is based on comparison of the staining of two (or more) independent antibodies directed towards independent epitopes …
WebPBS, pH 7.4, containing 0.1% sodium azide. General Product Property. Product Overview. Anti-Granulin (GRN) Antibody Pair Set. Capture Antibody: Rabbit Polyclonal IgG. … Webantibodies can be tested for self-binding within 2 h, rather than a few days. This high throughput is contributed partly by the design of the Octet® RED384, where 16 channels are available for data collection simultaneously. Furthermore, only 15 ug of each antibody is necessary for this assay, making CSI-BLI even
WebJun 6, 2024 · This rabbit polyclonal antibody, GR (M-20): sc-1004, has been discontinued and is no longer available. We highly recommend as an alternative, our mouse …
WebJan 12, 2024 · To explore antibody-mediated pharmacological modulation of TREM2-dependent microglial states, we identified antagonistic TREM2 antibodies. Treatment of macrophages from GRN-FTLD patients with these antibodies led to reduced TREM2 signaling due to its enhanced shedding. Furthermore, TREM2 antibody-treated PGRN … high tea intratuin halsterenWebGRN, also known as PGRN or PCDGF, is a cysteine-rich protein of 68.5 kDa that is typically secreted into a highly glycosylated 88 kDa form. … how many days until july 11WebThe assay will exclusively recognize both natural and recombinant Ms Progranulin. The Mouse Progranulin solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. high tea intratuin utrechtWebFind grn and related products for scientific research at MilliporeSigma. US EN. Applications Products Services Support. Advanced Search. Structure Search. Search Within. Products Technical Documents Site Content Papers Genes Chromatograms. Shipping. Ships Today (4) Product Category. antibodies (11) ... how many days until judgement dayWebProduct Specific Information. MA1-510 detects glucocorticoid receptor (GR) from human, mouse, rat, guinea pig, rabbit, sheep and yeast samples. This antibody does not react with primate, avian or amphibian GR. MA1-510 … how many days until july 10WebGoat anti Human GRN antibody recognizes GRN, also known as progranulin, granulin-3, proepithelin or PEPI . Granulins are a family of secreted, glycosylated peptides that … high tea inner westWebAlthough Grn R493X/R493X mice had detectable Grn mRNA (∼5–10% of wild-type levels), we did not detect the truncated progranulin R493X protein (∼54 kDa) in Western blots using an antibody that recognizes amino acids 198–214 and is able to detect the truncated progranulin R493X protein when this protein is overexpressed in cells . how many days until january the first