Some pharmacological research on gambogic acid has been conducted in vitro and in laboratory animals, but there are no proven clinical effects in humans. In studies conducted with mice and transplanted tumors (from human lung carcinoma SPC-A1 cells), tumor growth remained suppressed for up to 21 days during treatment with gambogic acid. The ratio of relative tumor volume (RTV) for the treated group of mice to the control group indic… WebJan 10, 2024 · Gambogic acid is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic acid inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM. Properties Articles 29 Spectrum Names Gambogic Acid Biological Activity Chemical & Physical Properties MSDS
DGIdb - GAMBOGENIC ACID Drug Record
WebOct 9, 2007 · Gambogic acid (GA) is the major active ingredient of gamboge, a brownish to orange resin exuded from the Garcinia hanburryitree in southeast Asia. The resin has been used in traditional Chinese medicine for the treatment of cancers (15). WebApr 1, 2024 · Gambogenic acid protected renal tubular epithelial cells against high glucose-induced inflammation and pyroptosis through suppression of AMPK–TXNIP pathway, providing a potential strategy for the prevention of diabetic nephropathy. Downloads Abstract 296 PDF Downloads 318 HTML Downloads 290 XML Downloads 13 References bolehills bmx track
A novel dual sensitive polymer-gambogic acid conjugate: …
WebJul 3, 2024 · Gambogic acid, a common traditional Chinese medicine and widely distributed throughout South China, Vietnam, Cambodia, and Thailand. It is prenylated xanthone which is the significant bioactive... WebSep 1, 2024 · The molar mass of neogambogic acid is 646.77 g·mol−1 and its molecular formula is C38H46O9. It appears as yellow crystalline, since it’s in large amount in the original ingredients, the extraction process is simple and low-cost, showing significant value of research and develop- ment [3]. WebGambogic acid C38H44O8 CID 5353639 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … gluten free top golf