2024 Fls2 pub12 pub13

Fls2 pub12 pub13

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August undefined, 2024

WebJun 17, 2011 · Flagellin strongly enhanced the interaction of PUB13 and FLS2, providing key evidence that the association had a possible role in signaling. PUB12, a close homolog of PUB13, also associated with … WebJul 13, 2024 · The ARM domains of PUB12/13 are essential for interaction with FLS2–BAK1 complex and phosphorylation by BAK1 ( Zhou et al., 2015a ). In vitro ubiquitination assay showed that PUB12 and PUB13 specifically polyubiquitinate FLS2, but not BAK1 and BIK1, which promotes the degradation of FLS2 ( Lu et al., 2011 ).

dominant negative ARM domain uncovers multiple functions of PUB13 …

WebOct 21, 2024 · PUB13 is an active E3 ubiquitin ligase and that the intact U-box domain is required for the E3 ligase activity. study has revealed a unique regulatory circuit of direct ubiquitination and turnover of FLS2 by BAK1-mediated phosphorylation and recruitment of specific E3 ligases (PUB12,PUB13) for attenuation of immune signaling WebMay 8, 2024 · The Arabidopsis PUB13 has been shown to attenuate the pattern recognition receptor FLS2-mediated immune signaling by ubiquitinating FLS2 and consequently promoting its degradation by the 26S proteasome. Nevertheless, the cognate ubiquitin-conjugating enzymes (E2) with which PUB13 acts to modulate FLS2-mediated PTI are … trade your books amazon

PUB12 armadillo/beta-catenin repeat protein [Arabidopsis …

http://biochemistry.tamu.edu/wp-content/uploads/sites/104/2016/03/FLS2_Ubiq_Science_2011.pdf WebA proposed model of PUB12/13-mediated ubiquitination of FLS2 in the attenuation of flagellin signaling. Source publication Direct Ubiquitination of Pattern Recognition Receptor FLS2 Attenuates... WebPharmacological inhibition of poly(ADP-ribose) polymerase (PARP) or loss of Arabidopsis thaliana PARG1 (poly(ADP-ribose) glycohydrolase) disrupt a subset of plant defenses. In the present study we examined the impact of altered poly(ADP-ribosyl)ation the saint raw

Fig. S11. A proposed model of PUB12/13-mediated …

U-Box E3 Ligase SPL11/PUB13 Is a Convergence Point of Defense …

Web微信公众号植物生物技术Pbj介绍：本公众号致力于植物生物技术领域重要进展的推介，由 Plant Biotechnology Journal杂志（2024年影响因子13.3，植物学研究型Top3 期刊）官方授权，华中农业大学为运营主体，PBJ杂志执行主编金双侠教授担任责任编辑；Current Biology 研究揭示植物受体激酶的免疫信号传导机制！ WebThe data are shown as means T SEs from three replicates. Asterisk indicates a significant difference with P < 0.05 when compared with data from WT plants. (E) PUB12 and PUB13 promote FLS2 degradation. the saint reboot updateWebNov 28, 2024 · Consequently, FLS2 is ubiquitinated by PUB12/PUB13 and then degraded through a 26S proteasome pathway. In a similar manner, rice PRR Xa21 is negatively regulated by the protein phosphatase 2C and ubiquitinated by the RING-finger ubiquitin E3 ligase XB3 . However, in contrast to PUB12/PUB13, XB3 positively regulates Xa21 … trade your bets review

"WebPUB12/13 then polyubiquitinate the cytosolic domain of FLS2 and promote 26 S proteasome-dependent FLS2 degradation, thereby down-regulating the immunity … " - Fls2 pub12 pub13

Fls2 pub12 pub13

WebApr 11, 2015 · The protein levels of FLS2, PUB13, and ARM were detected by α-HA, α-FLAG, or α-GFP WB, respectively. (D) Ectopic expression of PUB13ARM inhibits flg22 … WebBAK1 phosphorylates PUB12 and PUB13 and is required for FLS2-PUB12/13 association. PUB12 and PUB13 polyubiquitinate FLS2 and promote flagellin-induced FLS2 degradation, and the pub12 and pub13 mutants displayed elevated immune responses to …

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WebMay 8, 2024 · The Arabidopsis PUB13 has been shown to attenuate the pattern recognition receptor FLS2-mediated immune signaling by ubiquitinating FLS2 and consequently … WebBAKI phosphorylates PUB12 and PUB13 and is required for FLS2-PUB12/13 association. PUB12 and PUB13 polyubiquitinate FLS2 and promote flagellin-induced FLS2 degradation, and the publ2 and publ3 mutants displayed elevated immune responses to flagellin treatment. Our study has revealed a unique regulatory circuit of direct ubiquitination

WebMay 31, 2024 · PUB13 protein, Arabidopsis Ubiquitin-Protein Ligases Protein Kinases constitutive differential growth 1 protein, Arabidopsis FLS2 protein, Arabidopsis CERK1 protein, Arabidopsis Protein Serine-Threonine Kinases MAP Kinase Kinase Kinases MEKK1 protein, Arabidopsis Supplementary concepts Botrytis cinerea WebApr 11, 2015 · Arabidopsis FLS2, the receptor for bacterial flagellin, activates immune signalling by association with its partner BAK1. Upon flagellin (flg22) perception, the plant U-box E3 ubiquitin ligases PUB12 and PUB13 complex with FLS2 in a BAK1-dependent manner, and ubiquitinate FLS2 for protein degradation, thereby down-regulating flagellin …

WebThe Arabidopsis pattern-recognition receptor Flagellin Sensing 2 (FLS2) recognizes bacterial flagellin and initiates immune signaling through association with BAK1. ... et al. Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination. Proc. Natl. Acad. Sci. USA 2024 ... WebApr 18, 2013 · Author Summary As a Pattern-Recognition Receptor (PRR) that detects conserved microbial molecules, FLS2 mediates the plant innate immunity responses …

WebNov 28, 2024 · The pub12 pub13 mutant exhibited enhanced chitin-induced immune responses such as ROS production, MAPK activation, and callose deposition. These …

Web植物受体激酶是细胞外刺激的关键传递因子，如有益或致病微生物的存在或分泌的信号分子。. 受体激酶受到许多翻译后修饰的调节。. 在这篇文章中，科研人员利用免疫受体激酶FLS2和EFR，表明在所有植物受体激酶中保守的半胱氨酸的S-酰化对功能至关重要 ... the saint regisWebPUB12 and PUB13 carry out the FLS2 ubiquitination after they are phosphorylated by BAK1, suggesting that BAK1 regulates the FLS2 degradation . Activity of the BAK1 and BIK1 kinases is negatively regulated by phosphatases, however this process may be attenuated upon perception of the pathogen-associated ligand. trade your cleverness for bewildermentWebFeb 14, 2024 · Similar to pub13 mutants, pub12/13 double mutants showed altered responses to CO8 elicitation in ROS production and MAP kinase phosphorylation ... the mechanism of PUB13 regulation of FLS2 and … trade your games for cashWebOct 20, 2015 · PUB12 and PUB13, two highly homologous U-box E3 ligases, are involved in the regulation of FLS2 turnover 29, and PUB13 is also involved in defence response, cell death and flowering 30. trade your car in while you still owe moneyWebAs previously discussed, PUB12/PUB13-mediated ubiquitination of FLS2 is expected to modulate its intracellular trafficking (Lu et al., 2011). Since degradation of integral membrane proteins is mediated by the vacuole, … the saint regis bora boraWebFLS2 is ubiquitinated by two closely related plant U-box E3 ubiquitin ligases, PUB12 and PUB13, and subjected to degradation (Lu et al., 2011). PUB12 and PUB13 interact with BAK1, and are recruited to FLS2 on ﬂg22 perception. BAK1 phosphorylates PUB12 and PUB13 directly,and is required for FLS2 and PUB12/13 association. the saint regis bermudaWebOct 21, 2024 · Encodes a U-box E3 ubiquitin ligase involved in ubiquitination of pattern recognition receptor FLS2. NEW Try the new Gene table Try the new Transcript table. … trade your gift card online