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Elongin-cullin-socs-box protein

WebNov 5, 2013 · The tumor suppressor VHL (von Hippel-Lindau) protein is a substrate receptor for Ubiquitin Cullin Ring Ligase complexes (CRLs), containing a BC-box domain that associates to the adaptor Elongin B/C. VHL targets hypoxia-inducible factor 1α to proteasome-dependent degradation. Gam1 is an adenoviral protein, which also … WebDescription: Homo sapiens TUB like protein 4 (TULP4), transcript variant 1, mRNA. (from RefSeq NM_020245) Gencode Transcript: ENST00000367097.8 Gencode Gene: ENSG00000130338.13 Transcript (Including UTRs)

The structure and regulation of Cullin 2 based E3 …

WebCullin-5; Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating … WebTarget Information: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins Supplier Page. Supplier Page from antibodies-online for anti-RAB40C Antibody. covid and clabsi https://bexon-search.com

Pharos : Target Details - ASB9

WebNov 5, 2024 · The two most characteristic subfamilies of CRLs are the Skp1-cullin-F-box (SCF) and elongin-C-cullin-SOCS-box families, with the latter including the SOCS box … Web胎牛血清（杂交瘤细胞专用） sp2/0 小鼠骨髓瘤细胞. 佐剂乳化器 WebThe largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. Members of the ASB family include ASB-1 through ASB-18 and are involved in a variety of biological processes. ... (Elongin-Cullin-SOCS-box protein) E3 ubiquitin protein ligase complex. This complex mediates the ubiquitination ... bricklayer\u0027s 5w

Q9NRJ4 - UniProt

Category:anti-Cullin 5 Antibody from antibodies-online - biocompare.com

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Elongin-cullin-socs-box protein

ASB9 rabbit pAb-博奥龙Biodragon

WebMay 16, 2006 · By analogy with the von Hippel–Lindau (VHL) protein, which binds elongin BC to target hypoxia-inducible factor (HIF-1α) for proteasomal degradation (12, 13), it is … WebThe protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The y contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for …

Elongin-cullin-socs-box protein

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WebMay be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and … http://www.zen-bioscience.com/prod_view.aspx?IsActiveTarget=True&TypeId=163&Id=430195&FId=t3:163:3

http://www.biodragon.cn/cgkt/97479.html Web1993; Aso et al., 1995). In the ECS complex, Elongin C and the small ubiquitin-like protein Elongin B connect the cullins CUL2 or CUL5 to the substrate recognition module that …

http://www.biodragon.cn/plus/pdf.php?aid=97479 WebSubstrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent …

WebSubstrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent …

WebASB9 has a common structure, including a unique N-terminus, an ankyrin protein repeat domain, and a SOCS box domain. Whereas the SOCS box interacts with Elongin B, Elongin C, and Cullin 5 in the E3 ligase complex, the ankyrin protein repeat domain and the N-terminal disordered fragment interact with creatine kinase and are involved in … covid and care staffWebMar 9, 2016 · The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5 (Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing proteins have ubiquitin ligase activity mediated by the formation of a complex with the scaffold protein Cul5 and the RING domain protein Rbx2, and are thereby members … bricklayer\u0027s 5tWebFunction. May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. By similarity. bricklayer\u0027s 5xWebElongin BC and Cullin 5 are recruited directly to specific motifs in the SOCS box domain as part of a complex containing Ring box protein 2 (Rbx2) and a ubiquitin conjugating enzyme (E2) . Once the E3 ubiquitin ligase complex is assembled, target proteins bound through the SH2 domain undergo ubiquitination, leading to their proteasomal ... covid and cigarette smokersWebThe City of Fawn Creek is located in the State of Kansas. Find directions to Fawn Creek, browse local businesses, landmarks, get current traffic estimates, road conditions, and … covid and child poverty ukWebCullin-5; Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating … bricklayer\\u0027s 5xbricklayer\\u0027s 6